Rekombinanter CD3E (Muromonab Biosimilar) Antikörper

Produktnummer ABIN7795115

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD3E (Muromonab Biosimilar) in FACS und in vivo. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter CD3E (Muromonab Biosimilar) Antikörper (ABIN7795115)

Target: CD3E (Muromonab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD3E (Muromonab Biosimilar) Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), In vivo Studies (in vivo)

Güteklasse: Research Grade

Produktdetails anti-CD3E (Muromonab Biosimilar) Antikörper

Expressionssystem: Mammalian cells

Verwendungszweck: Muromonab Biosimilar, CD3 Monoclonal Antibody

Produktmerkmale: Muromonab Biosimilar uses the same protein sequences as the therapeutic antibody muromonab (OKT3). Muromonab (OKT-3) is a monoclonal anti-CD3 antibody used as immunosuppressive therapy in kidney, heart, and liver transplant patients. Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93 % monomeric immune globulin G type 2a (IgG2a). Muromonab binds to the T-cell surface glycoprotein CD3 epsilon chain. It appears to kill CD-3 positive cells by inducing Fc mediated apoptosis, antibody mediated cytotoxicity and complement-dependent cytotoxicity.

Aufreinigung: Protein A or G affinity column

Reinheit: >95 % by reducing SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1 mg of the protein by the LAL method

Immunogen: Human CD3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: > 3 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Details zu CD3E (Muromonab Biosimilar)

Target: CD3E (Muromonab Biosimilar)

Andere Bezeichnung: Muromonab Biosimilar

Substanzklasse: Biosimilar